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Posts Tagged ‘Cancer early detection’
Cancer Early Detection in 2013: Canary Foundation Leads the Way
January 9, 2013
Everyone here at Canary Foundation is looking forward to an exceptional year filled with challenges and scientific milestones for our program teams working on early cancer detection research in ovarian, breast, lung, pancreatic and prostate cancer.
We’re starting the year with a bang! We’ll host our first event of the year on February 8: our annual Ladies’ Luncheon featuring Jesse Draper (most famously known as the host of The Valley Girl Show), who will interview Canary Foundation Founder Don Listwin and Director of CCS and Chair of Radiology Dr. Sam Gambhir on the latest news in early cancer detection. It’s not too late to register!
This February is also the one-year anniversary of our Breast Cancer Early Detection Program. Canary Foundation scientists are collaborating with the Cancer Prevention Institute of California to study pre-diagnostic breast cancer samples for potential breast cancer biomarkers.
Another upcoming milestone is related to our ongoing research on microbubble imaging technology. We hope (and expect) to begin testing of microbubbles on patients at Stanford in 2013. Keep your eye out for news of impeding FDA approval of microbubble technology – we’ll be sure to share it with you when the news finally breaks!
You might have read that the Canary Center at Stanford will be moving to a new campus this year. The move to the Porter Street Campus is scheduled for late summer or early fall, to a facility about twice the size of our present building. The Canary Foundation offices will move also, due to Stanford University needing the current location for new uses. We’re all very excited about settling in to our new digs.
If you’ve ever been to a Canary Challenge ride, you’ll know what all the fuss is about! On September 28, 2013, we plan to host over 1,000 cyclists and raise $1 million or more for the Stanford Cancer Institute. The ride will start off from VMware in Palo Alto as it did in 2012. Teams of four or more are encouraged to sign up to participate, and we have a brand new 5K Ride/Walk to accompany the 50K, 75K, 100K and 100-mile rides this year. We encourage you to start building your teams now!
The annual Canary Early Detection Symposium will be hosted this year on October 15, 2013. This event brings together scientists, researchers and high tech industry to solve problems and collaborate in the field of early cancer detection in all of the Canary program areas.
It’s going to be a great year, and we invite you to book your calendars and join us as we raise money, celebrate successes, and forge our way ahead through new horizons in cancer early detection research!
Cancer Early Detection in 2012: Spirit of the Holidays!
December 13, 2012
We’re so grateful for all of the contributions by scientists, donors, and everyone who participated in the work of cancer early detection in 2012! We sincerely thank our donors, volunteers, scientists, and clinicians for their hard work and support- we couldn’t do it without you! Watch the slideshow below for a look back at all of Canary’s successes and milestones in 2012.
Early Cancer Detection Success Reaps Spirit Awards from Stanford Cancer Institute
December 12, 2012
Canary Founder Don Listwin Honored for Leadership in Early Detection of Cancer Research
Early detection of cancer research represents the heart and soul of our work. Last week, Stanford Cancer Institute bestowed two 2012 Spirit of Hope Awards upon Canary Foundation and on our founder, Don Listwin. We are so honored to be the recipient of this prestigious award, and are grateful for the opportunity to be publicly recognized for the work we do in the field of early detection.
“The commitment to identifying easy and affordable biomarkers to detect cancer when it is small is the driving force behind the work of Canary Foundation,” said Don. “Canary Foundation is honored to be recognized for this work. Within 10 years, we expect and hope to have the tools, technology, tests and the market to allow you to find cancer early where it is most curable.”
Our work is focused on funding scientific discovery into affordable early detection systems such as blood tests and ultrasound imaging in the fields of ovarian, pancreatic, prostate, breast and lung cancer.
“The major way we’re going to make an impact on cancer is early detection and we are thrilled to partner with Canary in this incredible enterprise,” said Stanford Cancer Institute Director Dr. Beverly Mitchell, MD, as she presented the two awards. More »
Early Cancer Detection Success Leads to Canary Featured as Charity of The Week
December 5, 2012
Early cancer detection results of Canary Foundation led to the honor of being named Charity of the Week by The Week magazine. Canary Foundation early cancer detection research focuses on lung, prostate, pancreatic, breast and ovarian early detection methodologies. The Week magazine is a domestic and international magazine discussing the latest developments in business, health, science, technology, the arts, culture, consumer products and travel.
“Canary Foundation is the world’s first nonprofit dedicated entirely to the development of testes for early cancer detection. Founded in 2004 by Don Listwin, a successful technology executive who lost his mother to misdiagnosed ovarian cancer, Canary Foundation funds collaborative research by teams of cancer experts, with the aim of one day being able to identify early-stage cancer through a simple blood test.
The vast majority of cancer research funding goes to treatments of the disease in later stages; less than 15 percent currently goes to early-detection efforts, when cancer is at its most treatable. Canary Foundation is currently funding early-stage tests for lung, ovarian, pancreatic, prostate, and breast cancers.”
Thank you so much to The Week Magazine for featuring Canary Foundation as a charity to watch!
Early Cancer Detection Update for National Cancer Institute and National Institute of Health
November 29, 2012
The National Cancer Institute, under the National Institute of Health, plays a crucial role in cancer research throughout the United States. As the nation’s “investment in cancer,” NCI has quite a bit of ground to cover. NCI’s annual budget is approximately $5 billion. In 2010, 7% of NCI’s budget was allocated to the Division of Cancer Prevention. The Early Detection Research Group is one of ten groups in this division, and the Early Detection Research Network (EDRN) is one of the division’s six major projects. This means that early detection research is receiving a fraction of that 7% budget.
Although early detection may not be their top focus, NCI has moved to make a more substantial investment in early detection research and technology, and is making headway in this area. Additionally, NCI has collaborated with Canary Foundation on early detection projects.
NCI started EDRN to bring together multiple institutions working on early detection research. Early detection has many facets and therefore requires the work of leaders from many fields. By working together, different institutions can more effectively facilitate advances in early detection science and translate these advances into clinical practice. Canary Foundation operates in this same way, organizing multi-institutional studies and moving studies towards clinical practice.
The NCI has also developed accelerated programs called SPORES, or Specialized Programs of Research Excellence. SPORE studies are set up to be short-term (five years or less) and high-impact where they can translate quickly to clinical use and improve the lives of humans. Their objective is to reduce cancer incidence and mortality, while seeking to better the quality of life for cancer patients. Several of Canary Foundation’s programs and researchers are involved in important SPORE work including our Ovarian and Prostate Cancer Programs. More »
Lung Cancer Early Detection Moves Forward at Canary Foundation
November 20, 2012
In keeping with Canary Foundation’s two-step process, the Canary Early Cancer Detection for Lung Cancer program’s goal is to develop a combined blood test and imaging approach to detect lethal lung cancer early, because early detection and treatment greatly enhance survival. The Canary Lung team is tackling the under-recognized area of lung cancer in non-smokers, seeking to understand why it develops and what the disease characteristics are in order to create screening tools for that disease.
Imaging for Lung Cancer Early Detection
CT screening* can reduce mortality from lung cancer, shown recently with the results of the National Lung Screening Trial, or NLST. Currently, when patients undergo a CT scan, it’s possible to see a problem spot, such as a lung nodule, but difficult to determine whether or not it is cancer. This presents a real opportunity to enhance the specificity of current imaging technology so it will be possible to determine if a spot isn’t or is cancer, and if so, whether it shows lethal characteristics.
Preliminary tests to improve the CT scan through molecular imaging have been very promising. A novel modified scan developed by Canary team members at Stanford uses new technologies to light up tumors so that their mass, and areas where they have spread, are clearly distinguishable in lung cancer patients. The technology will be tested for its specificity for early lung cancer (vs. benign conditions, such as scar tissue) in patients with lung nodules.
Biomarkers for Lung Cancer Early Detection
A blood biomarker test, used in combination with imaging, may also provide the specificity needed for accurate lung cancer screening. In line with Canary’s innovative and collaborative model, the Canary lung team has worked closely with five other organizations on a project to develop lung cancer biomarkers funded jointly by the National Cancer Institute (NCI). The most promising biomarkers from a comparison study in Vancouver are being selected.
The next step is to conduct a validation study of these biomarkers on carefully collected samples from the PLCO (Prostate, Lung, Colorectal, Ovarian) Screening Trial, a large randomized trial designed and sponsored by the NCI, to determine the effects of screening on cancer-related mortality.
If these biomarkers perform well on the PLCO samples, they will proceed through progressively more rigorous validation studies. Ultimately, blood biomarkers will be tested in combination with imaging in people currently getting screened for lung cancer, to validate the best approach for detecting lung cancer early and potentially saving lives.
*A computed tomography (CT) scan uses X-rays to make detailed pictures of structures inside the body.
Founders Expedite Change
October 30, 2012
Founders of nonprofit organizations are motivated to make a big difference where they see a problem in society. They come to understand there is a great need that only a nonprofit can fill. They allocate resources into starting the nonprofit and to developing a community that will help further the mission and resolve the problem. Canary Foundation was conceived by founder Don Listwin, who gives his all to generating affordable and easy early cancer detection biomarkers and imaging tools as part of Canary Foundation’s mission.
If you look at the history of philanthropy, you may be surprised to learn how far back this idea goes, and marvel at the rich environment of direct services, research, innovation, education, culture and arts the nonprofit sector has spawned. We can trace this idea as far back as Plato, the ancient Greek philosopher who donated his farm to his nephew upon his death in 347 A.D., to fund students and faculty in the Academy of Athens he founded. More »
Early Detection Tool Mass Spectrometers Explained by Dr. Mark Stolowitz
October 25, 2012
Dr. Mark Stolowitz, Director of the Proteomics Core Facility, tells us about Mass Spectrometers and how they’re used for cancer early detection research.
Ride On! Celebrating the Canary Challenge for Cancer Research
October 10, 2012
On September 29, 500 riders convened at VMware in Palo Alto to set off on the Canary Challenge ride. All together, we raised $514,000 to benefit the Stanford Cancer Institute and the Canary Center at Stanford. This year’s numbers far surpassed last year’s ride of 344 riders and $300,000 raised. Take note: we have even bigger plans for next year!
Throughout the day, there were countless high points to celebrate. Here are just a few to highlight:
- Team spirit! This year, 32 teams rode together, many of who had trained together for months in advance. The feeling of camaraderie and support was palpable in the air
- Social media: Throughout the day, riders tweeted and interacted with our social media team as they rode, encouraging fellow riders, sharing their experiences, and spreading the word about the Canary Challenge
- Canary Chicks: Every year, the Canary Chicks make a splash! With their telltale boas and exuberant spirit, they put a smile on everyone’s face as they passed
- Creativity: One rider wore wings with each layer representing the number of donors he had- what a creative way to demonstrate the commitment and support of others
- Support: The high school student volunteers cheering on riders at the finish line. They made every rider feel like a champion. Kudos to all of our volunteers who supported riders with food, drink and cheering
- Accomplishment: Seeing the smiles of the first time 100-mile riders as they finished and arrived back at the Village. Their sense of accomplishment and pride was a true pleasure to witness
It was a great opportunity to have fun while making a real difference by fundraising for cancer early detection research. The funds raised directly affect the ability of the Stanford Cancer Institute to fund research and innovative clinical programs.
If you missed the event, check out professional photos from the ride, as well as images from the Canary social media community.
Save the date for Canary Challenge 2013, to be held on September 28. It’s never too early to start building your teams and start training!
What Will Cancer Early Detection Look Like?
September 18, 2012
Co- authored by Abbie Lieberman.
Imagine the year is 2030. Jane Doe has been feeling under the weather and is experiencing unfamiliar stomach pain. Her doctor sends her a portable, at-home screening kit that can test for multiple conditions including a variety of cancers. She takes a picture of the results using her smart device and sends them off to her doctor. A day later in the clinic, her doctor informs her that she has the earliest stages of ovarian cancer detectable. In this future time, Jane’s cancer cells are removed quickly and she is out of danger. In such a world, cancer is found early and is eliminated or reduced to a chronic illness, rarely being a fatal disease. Jane is closely monitored from this time forward and she goes on to live a long and happy life.
When cancer early detection tools become a reality, cancer screenings will change drastically and so will the impact of this disease on human life. Cancer could be re-categorized to become a condition or a disease swiftly dealt with, with fewer side effects or damage to the body. However, at-home tests to detect cancer early could be a long way off in the future. Is there something we can believe in without waiting for the Jane Doe scenario to come about?
In the more near-term, Canary researchers foresee important steps becoming practiced in our lifetime. A patient will most likely go into a doctor’s office, and get an extensive panel of blood work done at an annual exam. If the results are positive, an imaging test will be conducted to determine exactly where the cancer cells are. We already know this truth: when found early, a tumor can be removed or treated before it spreads. The patient’s survival rate increases to 90% (generalized) compared to the 10% survival rate when found late (today’s norm). More »
